Lactose Permease

By: Stephanie McClure & Meghan Lee

Views

Original Settings

Spin On

Spin Off

Space-filled Model

Ribbon Structure:

Electrostatic Surface Potential: The more electrostatic regions of the protein are seen in the outer areas.

Cartoon Structure with Hydrogen Bonds

Colipase Backbone

Ligand

C-terminus or N-terminus

Cartoon Structure:

Hydrogen Bonds

Amino Acid Groups:

Color Groups: The vast majority of this protein consists of alpha-helices

Color Structure

Lipophilicity Surface Potential:  (takes a moment to load)

Color Temperature:  The surface residues are more mobile, colored red, progressing to more immobile blue fragments.

Lactose Permease is produced by the lac Y gene, and transports the ß-galactoside into E. coli.  This protein has 12 α-helices which cover the membrane of the cell.  The ligand is TDG, a substrate that activates this protein.