1. To understand how the kidneys allow osmoregulation and excretion of wastes
Introduction
osmoregulation: an example of homeostasisosmoregulation & excretion: both take place in kidney
Osmoregulation
in marine environments
osmoconformers: blood has same osmolarity as environmentosmoregulation:
fish: blood more dilute than environment -- drink seawater, excrete saltssharks: blood more concentrated than environment -- don't drink seawater, excrete dilute urine
in freshwater environments
all osmoregulatefish: don't drink, eat food with solutes, actively transport salts in via gills, excrete dilute urine
in terrestrial environments
water inputs: food, drink, metabolismoutputs: evaporation, feces, urine, etc.
need to conserve water, but need to excrete nitrogenous wastes
ammonia (most aquatic orgs) -- highly toxic, must get rid of right away at low conc.urea (mammals, adult amphibians, sharks) -- less toxic, can concentrate
uric acid (birds, insects, some reptiles) -- very low solubility (water efficient), requires lots of energy to make
Osmoregulation and excretion in humans
our kidneys must: osmoregulate, excrete urea and conserve water
structureclick here to see the structure of the human kidneyfunction
3 processes:filtration: removal of substances from blood, creating a filtratewater, salts, glucose, vitamins, urea, etc.secretion: addition of substances from blood to filtrate
poisons, drugspH balance
reabsorption: putting some stuff in the filtrate back into the blood
water, salts, glucose, vitamins, etc.the process:
glomerulus: filtrationdistal and proximal tubules: secretion and reabsorption
loop of Henle and collecting duct: water conservation
control of osmoregulation
ADH: responds to changes in blood osmolarity -- responds by altering urine osmolarity/volume
click here to go to osmoregulation vocabulary
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